May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.

Description
Rabbit polyclonal antibody to AS160

Applications 
WB.

Immunogen 
AS160 Antibody detects endogenous levels of total AS160.

Reactivity 
Human, Mouse, Rat.

Molecular weight
160kDa; 147kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
AS160 

Synonyms 
Acrg embryonic lethality (mouse) minimal region ortholog; Acrg embryonic lethality minimal region ortholog; Acrg embryonic lethality mouse minimal region ortholog; Akt substrate of 160 kDa; AS 160; AS160; BUB2; CDC16; KIAA0603; NIDDM5; TBC (Tre 2 BUB2 CDC16) domain containing protein; TBC Tre 2 BUB2 CDC16 domain containing protein; TBC1 D4; TBC1 domain family member 4; Tbc1d4; TBCD4_HUMAN; Tre-2;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
O60343

Western blot analysis of extracts from HepG2 cells(heat-shock treatment), using AS160 Antibody. The lane on the left was treated with blocking peptide....

Western blot analysis of extracts from Serum-starved EC304 cells, using AS160 Antibody. The lane on the left was treated with blocking peptide....