Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.

Description
Rabbit polyclonal antibody to ARX

Applications 
WB, IF, ICC.

Immunogen 
ARX Antibody detects endogenous levels of total ARX.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(100%), Sheep(%), Rabbit(%), Dog(%)

Molecular weight
55 KD; 58kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ARX

Synonyms 
Aristaless related homeobox gene; Aristaless-related homeobox; Arx; ARX_HUMAN; Homeobox protein ARX; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRXS1; phox2a; PRTS;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q96QS3

Western blot analysis of extracts from Mouse brain lysates, using ARX antibody....

ab15531 staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. Samples were then incubated with primary Ab(ab15531) and mouse anti-beta tubulin for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody. The nuclear counter stain is DAPI (blue)....

Fig. 4. The expression of pancreatic proteins that participate in islet cell function of adult F1 mice. The data were shown as the mean ± SE and analyzed with SPSS 19.0 software. Significant difference (p < 0.05) was tested using one-way ANOVA (Duncan...

Fig. 6.| Immunofluorescence analysis of Pdx1 and Arx expression in islet cells of male mice exposed to Aroclor 1254 for 60 days. (A) Representative images of triple staining for insulin (green), Pdx-1 (red), and DAPI (blue) on fixed, paraffin-embedded pancreas sections. (B) Percentage of Pdx-1 positive data are presented as mean ± SE (n = 3). (C) Representative images of triple staining for glucagon (green), Arx (red), and DAPI (blue) on fixed, paraffin-embedded pancreas sections. (D)Percentage of Arx positive data are presented as mean ± SE (n = 3). Means of exposures not sharing a common letter are significantly different at P < 0.05 as assessed by one-way ANOVA followed by the Duncan test. Scale bar = 50 μm....