Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (By similarity). Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles (By similarity). May play a role in glucose uptake.

Description
Rabbit polyclonal antibody to Arrdc4

Applications 
WB, IF, ICC, IHC.

Immunogen 
Arrdc4 Antibody detects endogenous levels of total Arrdc4.

Reactivity 
Human, Mouse.
可预测：Pig(91%), Bovine(%), Horse(%), Sheep(%), Dog(%)

Molecular weight
45kDa; 45kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
Arrdc4

Synonyms 
ARRD4_HUMAN; ARRDC 4; Arrdc4; Arrestin domain containing protein 4; Arrestin domain-containing protein 4; FLJ36045;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q8NCT1

Western blot analysis of extracts from K562, using Arrdc4 Antibody. The lane on the left was treated with blocking peptide....

ab12145 at 1/100 staining Rat heart tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody....