Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.

Description
Rabbit polyclonal antibody to ARPP21

Applications 
WB, IF, ICC, IHC.

Immunogen 
ARPP21 Antibody detects endogenous levels of total ARPP21.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(100%), Horse(%), Sheep(%), Rabbit(%), Dog(%), Chicken(%)

Molecular weight
80 KD; 89kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ARPP21

Synonyms 
0710001E13Rik; AI853636; ARP21_HUMAN; ARPP-21; ARPP21; cAMP regulated phosphoprotein, 21kDa; cAMP-regulated phosphoprotein 21; cAMP-regulated phosphoprotein, 21-KD; Cyclic AMP-regulated phosphoprotein; Cyclic AMP-regulated phosphoprotein, 21; D9Bwg1012e; FLJ32997; MGC109368; OTTHUMP00000161358; OTTHUMP00000208635; OTTHUMP00000208636; OTTHUMP00000208637; OTTHUMP00000208638; OTTHUMP00000208639; OTTHUMP00000208640; OTTHUMP00000208641; OTTHUMP00000208646; OTTHUMP00000208648; OTTHUMP00000208651; OTTHUMP00000208652; OTTHUMP00000208653; OTTHUMP00000208657; Ppp1r1c; Ppp1r1cl; R3H domain containing 3; R3HDM3; RCS; Regulator of calmodulin signaling; RGD1307208; RGD1307215; Tarpp; Thymocyte cAMP-regulated phosphoprotein;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q9UBL0

Western blot analysis of extracts from 293t, using ARPP21 Antibody. The lane on the left was treated with blocking peptide....

ab14730 at 1/100 staining Rat spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody....

ab14730 staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. Samples were then incubated with primary Ab(ab14730 1:200) and mouse anti-beta tubulin for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody. The nuclear counter stain is DAPI(blue)....