Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.

Description
Rabbit polyclonal antibody to ARMCX1

Applications 
WB, IF, ICC, IHC.

Immunogen 
ARMCX1 Antibody detects endogenous levels of total ARMCX1.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(82%), Sheep(%), Dog(%)

Molecular weight
49kDa; 49kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ARMCX1

Synonyms 
ARMCX 1; AD032; ALEX1; ARM protein lost in epithelial cancers on chromosome X 1; Arm protein lost in epithelial cancers X chromosome 1; Armadillo repeat containing X linked 1; Armadillo repeat containing X linked protein 1; Armadillo repeat-containing X-linked protein 1; ARMCX1; ARMX1_HUMAN; Protein ALEX1;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q9P291

Western blot analysis of ARMCX1 using HeLa whole cell lysates...

ab12141 at 1/100 staining Rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody....

ab12141 staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. Samples were then incubated with primary Ab(ab12141 1:200) and mouse anti-beta tubulin for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody. The nuclear counter stain is DAPI(blue)....