Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidence is required to confirm these data.

Description
Rabbit polyclonal antibody to ARL13B

Applications 
WB, IHC.

Immunogen 
ARL13B Antibody detects endogenous levels of total ARL13B.

Reactivity 
Human, Mouse, Rat, Dog.
可预测：Pig(100%), Zebrafish(%), Bovine(%), Horse(%), Sheep(%), Rabbit(%), Chicken(%)

Molecular weight
40-48 kDa, 66 kDa; 49kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ARL13B

Synonyms 
ADP ribosylation factor like 13B; ADP ribosylation factor like 2 like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; AR13B_HUMAN; arl13b; ARL2-like protein 1; ARL2L1; JBTS8;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q3SXY8

Western blot analysis of extracts from 3t3, using ARL13B Antibody. Lane 1 was treated with the blocking peptide....

Western blot analysis of extracts from Hybridoma cells, using ARL13B Antibody. The lane on the left was treated with blocking peptide....