Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.

Description
Rabbit polyclonal antibody to ARHGDIG

Applications 
WB, IF, ICC, IHC.

Immunogen 
ARHGDIG Antibody detects endogenous levels of total ARHGDIG.

Reactivity 
Human.
可预测：Pig(89%), Bovine(%)

Molecular weight
25 KD; 25kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ARHGDIG

Synonyms 
Arhgdig; GDIR3_HUMAN; OTTHUMP00000067353; OTTHUMP00000194914; Rho GDI 3; Rho GDI gamma; Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP dissociation inhibitor 3; Rho GDP dissociation inhibitor gamma; Rho GDP-dissociation inhibitor 3; Rho-GDI gamma; RHOGDI 3; RhoGDI gamma; RHOGDI3;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q99819

Western blot analysis of extracts from A549 cells, using ARHGDIG Antibody. The lane on the left was treated with blocking peptide....

Western blot analysis of extracts from A549/Jurkat cells, using ARHGDIG antibody....

ab15281 at 1/100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-rabbit antibody was used as the secondary antibody....