Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity).

Description
Rabbit polyclonal antibody to Aquaporin 7

Applications 
WB, IF, ICC, IHC.

Immunogen 
Aquaporin 7 Antibody detects endogenous levels of total Aquaporin 7.

Reactivity 
Human, Mouse.
可预测：Dog(82%)

Molecular weight
37 kDa; 37kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
Aquaporin 7

Synonyms 
AQP 7; AQP 7L; AQP 9; AQP-7; Aqp7; AQP7_HUMAN; AQP7L; AQP9; AQPap; Aquaglyceroporin-7; Aquaporin 7 like; Aquaporin adipose; Aquaporin-7; Aquaporin-7-like; Aquaporin7; MGC149555; MGC149556;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
O14520

Western blot analysis of extracts from various samples, using Aquaporin 7 Antibody. Lane 1: EC304 cells, treated with blocking peptide; Lane 2: EC304 cells; Lane 3: P19 cells....

ab17620 at 1/100 staining mouse colorectal tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-rabbit antibody was used as the secondary antibody....

ab17620 at 1/100 staining rat colorectal tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-rabbit antibody was used as the secondary antibody....

ab17620 staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. Samples were then incubated with primary Ab(ab17620 1:200) and mouse anti-beta tubulin for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody. The nuclear counter stain is DAPI(blue)....