Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

Description
Rabbit polyclonal antibody to Antizyme inhibitor 1

Applications 
WB, IHC.

Immunogen 
Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(100%), Bovine(%), Sheep(%), Rabbit(%), Dog(%), Chicken(%), Xenopus(%)

Molecular weight
49.5 kDa; 50kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
Antizyme inhibitor 1 

Synonyms 
Antizyme inhibitor 1; AZI; Azin1; AZIN1_HUMAN; OAZI; OAZIN; ODC1L; Ornithine decarboxylase antizyme inhibitor;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
O14977

Western blot analysis of extracts from various samples, using Antizyme inhibitor 1 Antibody. Lane 1: Myeloma cells, treated with blocking peptide; Lane 2: Myeloma cells; Lane 3: Hela cells; Lane 4: B16F10 cells....