Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Description
Rabbit polyclonal antibody to ALS2CR8
Applications
WB, IF, ICC, IHC.
Immunogen
ALS2CR8 Antibody detects endogenous levels of total ALS2CR8.
Reactivity
Human, Mouse.
可预测:Pig(94%), Bovine(%), Horse(%), Sheep(%), Rabbit(%), Dog(%), Chicken(%), Xenopus(%)
Molecular weight
70,85 KD; 81kD(Calculated).
Host species
Rabbit
Ig class
Immunogen-specific rabbit IgG
Purification
Antigen affinity purification
Full name
ALS2CR8
Synonyms
Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium response factor; Calcium-response factor; Calcium-responsive transcription factor; CaRF; CARTF_HUMAN; Testis development protein NYD SP24; Testis development protein NYD-SP24;
Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Swissprot
Q8N187