This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

Description
Rabbit polyclonal antibody to ADRA1A

Applications 
WB, IF, ICC.

Immunogen 
ADRA1A Antibody detects endogenous levels of total ADRA1A.

Reactivity 
Human, Mouse, Rat.
可预测：Rabbit(89%)

Molecular weight
51 KD; 51kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ADRA1A

Synonyms 
ADA1A_HUMAN; ADRA1A; Adra1c; ADRA1L1; Adrenergic alpha1A receptor; Adrenergic alpha1C receptor; Adrenergic receptor alpha 1a; Adrenergic receptor alpha 1c; Adrenergic, alpha 1A , receptor variant 1; Adrenergic, alpha 1A , receptor variant 11; Adrenergic, alpha 1A , receptor variant 3; Adrenergic, alpha 1A , receptor variant 5; Adrenergic, alpha 1A , receptor variant 8; Adrenoceptor alpha 1A; Alpha 1A adrenoreceptor; Alpha 1C adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1A adrenoceptor; Alpha-1A adrenoreceptor; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c; Alpha1A adrenergic receptor; ALPHA1AAR; G protein coupled receptor;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
P35348

Western blot analysis of extracts from rat brain, using ADRA1A antibody....

Western blot analysis of extracts from mouse brain, using ADRA1A Antibody. Lane 1 was treated with the antigen-specific peptide....