Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT. The action of this enzyme is not yet clear (Probable). It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).

Description
Rabbit polyclonal antibody to ADCK1

Applications 
WB, IF, ICC, IHC

Immunogen 
ADCK1 Antibody detects endogenous levels of total ADCK1.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(100%), Zebrafish(80%), Bovine(91%), Horse(91%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(90%)

Molecular weight
61kDa; 61kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
ADCK1

Synonyms 
2610005A10Rik; aarF domain containing kinase 1; ADCK 1; ADCK1; ADCK1_HUMAN; BOS_11212; FLJ39600; MGC142877; Uncharacterized aarF domain containing protein kinase 1; Uncharacterized aarF domain-containing protein kinase 1;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
Q86TW2

Western blot analysis of extracts from Rat heart, using ADCK1 Antibody. The lane on the left was treated with blocking peptide....

ab10386 at 1/100 staining Human colorectal cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody....

ab10386 at 1/100 staining Human colorectal cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody....

ab10386 at 1/100 staining Human ovarian cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody....

ab10386 at 1/100 staining Mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody....