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Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins.
May act as alpha-secretase for amyloid precursor protein (APP).
Description
Rabbit polyclonal antibody to ADAM9
Applications
WB.
Immunogen
ADAM9 Antibody detects endogenous levels of total ADAM9.
Reactivity
Human, Mouse, Rat.
可预测:Pig(89%), Horse(100%), Rabbit(90%)
Molecular weight
91kDa, 70 kDa; 91kD(Calculated).
Host species
Rabbit
Ig class
Immunogen-specific rabbit IgG
Purification
Antigen affinity purification
Full name
ADAM9
Synonyms
A disintegrin and metalloproteinase domain 9; ADAM 9; ADAM metallopeptidase domain 9; Cellular disintegrin related protein; Cone rod dystrophy 9; CORD9; Disintegrin and metalloproteinase domain 9; Disintegrin and metalloproteinase domain containing protein 9; KIAA0021; MCMP; MDC 9; MDC9; Meltrin gamma; Metalloprotease disintegrin cysteine rich protein 9; Mltng; Myeloma cell metalloproteinase;
Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Swissprot
Q13443
Western blot analysis of extracts from EC304, using ADAM9 Antibody. The lane on the left was treated with blocking peptide. Observed bands: 70 kDa....

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