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Fig. 1. GRIM-19 expression is related to CRC progression. (A) Expression of GRIM-19 transcript in CRC tissues versus adjacent normal tissues. The plotted data are from the GEPIA database. (B and C) Overall survival and disease-free survival among CRC patients with different GRIM-19 levels. The plotted data are from the GEPIA database. (D and E) The expression of GRIM-19 and p53 in primary normal colorectal (N) and CRC (T) tissues as analyzed by Western blot assays. (F and G) The expression of GRIM-19 in normal colorectal and CRC tissues was detected by IHC. Bar = 50 μ m. (H) The expression of GRIM-19 in CRC cell lines DLD-1, SW620, HT15, HCT116 and HCT-8 as analyzed by Western blot assays....
Fig. 4. Effect of resveratrol on the acetylation of FXR in HepG2 cells. (A) The interaction of SIRT1 with FXR. (B) The relative protein levels of Ac-FXR in different groups of HepG2 cells detected by IP....

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