Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways (By similarity). Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids (By similarity). Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
Description
Rabbit polyclonal antibody to ABHD6
Applications
WB, IF, ICC.
Immunogen
ABHD6 Antibody detects endogenous levels of total ABHD6.
Reactivity
Human, Mouse, Rat.
可预测:Pig(91%), Bovine(100%), Horse(82%), Sheep(91%), Rabbit(91%), Dog(100%)
Molecular weight
38 KD; 38kD(Calculated).
Host species
Rabbit
Ig class
Immunogen-specific rabbit IgG
Purification
Antigen affinity purification
Full name
ABHD6
Synonyms
0610041D24Rik; 2 arachidonoylglycerol hydrolase; AA673485; Abhydrolase domain containing 6; Abhydrolase domain containing protein 6; AV065425; Llipase protein; MGC94917;
Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Swissprot
Q9BV23