This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of TOR signaling.

Description
Rabbit polyclonal antibody to 5HT6 Receptor

Applications 
WB, IF, ICC

Immunogen 
5HT6 Receptor Antibody detects endogenous levels of total 5HT6 Receptor.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(100%), Bovine(100%), Horse(100%), Dog(100%)

Molecular weight
47 KD; 47kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
5HT6 Receptor

Synonyms 
5 HT 6; 5 HT6; 5 HT6R; 5 hydroxytryptamine (serotonin) receptor 6 G protein coupled; 5 hydroxytryptamine 6 receptor; 5 hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; 5-hydroxytryptamine receptor 6; 5HT 6; 5HT6R_HUMAN; HTR 6; Htr6; Serotonin receptor 6;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
P50406

Western blot analysis of extracts from Mouse liver, using 5HT6 Receptor Antibody. The lane on the left was treated with blocking peptide....

Western blot analysis of extracts from Mouse kidney, using 5HT6 Receptor Antibody. The lane on the left was treated with blocking peptide....