This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Description
Rabbit polyclonal antibody to 5HT3A receptor

Applications 
WB, IF, ICC, IHC

Immunogen 
5HT3A receptor Antibody detects endogenous levels of total 5HT3A receptor.

Reactivity 
Human, Mouse, Rat.

Molecular weight
55 kDa,; 55kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
5HT3A receptor

Synonyms 
5 HT 3; 5 HT3 receptor; 5 HT3A; 5 HT3A receptor; 5 HT3RA; 5 hydroxytryptamine (serotonin) receptor 3A; 5-HT-3; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT receptor; 5HT3 serotonin receptor; 5HT3A_HUMAN; 5HT3R; HTR3; Htr3a; Serotonin receptor 3A; Serotonin-gated ion channel receptor 3a; Serotonin-gated ion channel receptor;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
P46098

Western blot analysis of extracts from various samples, using 5HT3A receptor Antibody. Lane 1: A549 cells, blocked with antigen-specific peptides, Lane 2: A549 cells, Lane 3: Hela cells....

ab13653 staining Hela cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. Samples were then incubated with primary Ab(ab13653) and mouse anti-beta tubulin Ab(T0023) for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) Ab(Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) Ab(Green) were used as the secondary antibody. The nuclear counter stain is DAPI (blue)....