Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.

Description
Rabbit polyclonal antibody to 5 Lipoxygenase

Applications 
WB

Immunogen 
5 Lipoxygenase Antibody detects endogenous levels of total 5 Lipoxygenase.

Reactivity 
Human, Mouse, Rat.
可预测：Pig(89%), Bovine(89%), Sheep(89%), Rabbit(89%), Dog(89%)

Molecular weight
78kDa; 78kD(Calculated).

Host species 
Rabbit

Ig class 
Immunogen-specific rabbit IgG

Purification 
Antigen affinity purification

Full name 
5 Lipoxygenase 

Synonyms 
5 LO; 5 LOX; 5-lipoxygenase; 5-LO; 5-LOX; 5LOX; 5LPG; ALOX 5; Alox5; Arachidonate 5 lipoxygenase; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; Arachidonic acid 5 lipoxygenase; Leukotriene A4 synthase; LOG 5; LOG5; LOX5_HUMAN; MGC163204;

Storage
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Swissprot 
P09917

FIGURE 7 NDUFA4L2 regulated downstream p38-5-LO pathway may be an important mechanism for hypoxic pulmonary vascular remodelling. A, After interference with NDUFA4L2, Western blotting was used to detect the expression of p-ERK/ERK, p-p38/ p38, p-ERK/ERK in hypoxic HPASMCs; (B) After interference with NDUFA4L2, Western blotting was used to detect the expression of p-5-LO/5-LO in hypoxic HPASMCs. NC, negative control; Nor, normoxia; Hyp, hypoxia. *P < .05, **P < .01. n = 6. All of the values are denoted as mean ± SEM...