产品背景

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. (The background information is obtained from official databases and does not represent the product information.)

Name of antibody:
ACTB 
 

Immunogen:
Synthetic peptide of human ACTB 
 

Full name:
actin beta 
 

Synonyms:
BRWS1; PS1TP5BP1 
 

SwissProt:
P60709 
 

ELISA Recommended dilution:
5000-10000 
 

IHC positive control:
Human tonsil 
 

IHC Recommend dilution:
50-100 
 

WB Predicted band size:
42 kDa 
 

WB Positive control:
Mouse kidney tissue, Mouse brain tissue, 231 cell, Hela cell, 293T cell, HepG2 cell, NIH/3T3 cell lysates 
 

WB Recommended dilution:
1000-5000 

 

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ab100004(ACTB Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)...

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ab100004(ACTB Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)...

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-7: Mouse kidney tissue, Mouse brain tissue, 231 cell, Hela cell, 293T cell, HepG2 cell, NIH/3T3 cell lysates, Primary antibody: D110001(ACTB Antibody) at dilution 1/800, Secondary antibody: ab100004(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 5 seconds...