产品背景

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.

保存缓冲液
Ascitic fluid with 0.05% sodium azide and 40% glycerol 
 

运输条件
2-8°C 
 

靶点 Uniprot 登记号
P04406 
 

靶点基因 ID
2597 
 

靶点全称
glyceraldehyde-3-phosphate dehydrogenase 
 

靶点别名
G3PD; GAPD; HEL-S-162eP 
 

靶点研究领域
Metabolism, Cancer, Neuroscience 
 

亚型
IgG1 

 

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer and Human ovarian cancer tissue using ab100002(GAPDH Antibody) at dilution 1/150. (Original magnification: ×200)...

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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HUVEC cell and Human left lung tissue lysates, Primary antibody: ab100002(GAPDH Antibody) at dilution 1/1200, Secondary antibody: Goat anti mouse IgG at 1/5000 dilution, Exposure time: 3 minutes...